2023-03-14 更新
AugDiff: Diffusion based Feature Augmentation for Multiple Instance Learning in Whole Slide Image
Authors:Zhuchen Shao, Liuxi Dai, Yifeng Wang, Haoqian Wang, Yongbing Zhang
Multiple Instance Learning (MIL), a powerful strategy for weakly supervised learning, is able to perform various prediction tasks on gigapixel Whole Slide Images (WSIs). However, the tens of thousands of patches in WSIs usually incur a vast computational burden for image augmentation, limiting the MIL model’s improvement in performance. Currently, the feature augmentation-based MIL framework is a promising solution, while existing methods such as Mixup often produce unrealistic features. To explore a more efficient and practical augmentation method, we introduce the Diffusion Model (DM) into MIL for the first time and propose a feature augmentation framework called AugDiff. Specifically, we employ the generation diversity of DM to improve the quality of feature augmentation and the step-by-step generation property to control the retention of semantic information. We conduct extensive experiments over three distinct cancer datasets, two different feature extractors, and three prevalent MIL algorithms to evaluate the performance of AugDiff. Ablation study and visualization further verify the effectiveness. Moreover, we highlight AugDiff’s higher-quality augmented feature over image augmentation and its superiority over self-supervised learning. The generalization over external datasets indicates its broader applications.
PDF
点此查看论文截图
Regularized Vector Quantization for Tokenized Image Synthesis
Authors:Jiahui Zhang, Fangneng Zhan, Christian Theobalt, Shijian Lu
Quantizing images into discrete representations has been a fundamental problem in unified generative modeling. Predominant approaches learn the discrete representation either in a deterministic manner by selecting the best-matching token or in a stochastic manner by sampling from a predicted distribution. However, deterministic quantization suffers from severe codebook collapse and misalignment with inference stage while stochastic quantization suffers from low codebook utilization and perturbed reconstruction objective. This paper presents a regularized vector quantization framework that allows to mitigate above issues effectively by applying regularization from two perspectives. The first is a prior distribution regularization which measures the discrepancy between a prior token distribution and the predicted token distribution to avoid codebook collapse and low codebook utilization. The second is a stochastic mask regularization that introduces stochasticity during quantization to strike a good balance between inference stage misalignment and unperturbed reconstruction objective. In addition, we design a probabilistic contrastive loss which serves as a calibrated metric to further mitigate the perturbed reconstruction objective. Extensive experiments show that the proposed quantization framework outperforms prevailing vector quantization methods consistently across different generative models including auto-regressive models and diffusion models.
PDF Accepted to CVPR 2023
点此查看论文截图
Diffusion-Based Hierarchical Multi-Label Object Detection to Analyze Panoramic Dental X-rays
Authors:Ibrahim Ethem Hamamci, Sezgin Er, Enis Simsar, Anjany Sekuboyina, Mustafa Gundogar, Bernd Stadlinger, Albert Mehl, Bjoern Menze
Due to the necessity for precise treatment planning, the use of panoramic X-rays to identify different dental diseases has tremendously increased. Although numerous ML models have been developed for the interpretation of panoramic X-rays, there has not been an end-to-end model developed that can identify problematic teeth with dental enumeration and associated diagnoses at the same time. To develop such a model, we structure the three distinct types of annotated data hierarchically following the FDI system, the first labeled with only quadrant, the second labeled with quadrant-enumeration, and the third fully labeled with quadrant-enumeration-diagnosis. To learn from all three hierarchies jointly, we introduce a novel diffusion-based hierarchical multi-label object detection framework by adapting a diffusion-based method that formulates object detection as a denoising diffusion process from noisy boxes to object boxes. Specifically, to take advantage of the hierarchically annotated data, our method utilizes a novel noisy box manipulation technique by adapting the denoising process in the diffusion network with the inference from the previously trained model in hierarchical order. We also utilize a multi-label object detection method to learn efficiently from partial annotations and to give all the needed information about each abnormal tooth for treatment planning. Experimental results show that our method significantly outperforms state-of-the-art object detection methods, including RetinaNet, Faster R-CNN, DETR, and DiffusionDet for the analysis of panoramic X-rays, demonstrating the great potential of our method for hierarchically and partially annotated datasets. The code and the data are available at: https://github.com/ibrahimethemhamamci/HierarchicalDet.
PDF
点此查看论文截图
DDS2M: Self-Supervised Denoising Diffusion Spatio-Spectral Model for Hyperspectral Image Restoration
Authors:Yuchun Miao, Lefei Zhang, Liangpei Zhang, Dacheng Tao
Diffusion models have recently received a surge of interest due to their impressive performance for image restoration, especially in terms of noise robustness. However, existing diffusion-based methods are trained on a large amount of training data and perform very well in-distribution, but can be quite susceptible to distribution shift. This is especially inappropriate for data-starved hyperspectral image (HSI) restoration. To tackle this problem, this work puts forth a self-supervised diffusion model for HSI restoration, namely Denoising Diffusion Spatio-Spectral Model (\texttt{DDS2M}), which works by inferring the parameters of the proposed Variational Spatio-Spectral Module (VS2M) during the reverse diffusion process, solely using the degraded HSI without any extra training data. In VS2M, a variational inference-based loss function is customized to enable the untrained spatial and spectral networks to learn the posterior distribution, which serves as the transitions of the sampling chain to help reverse the diffusion process. Benefiting from its self-supervised nature and the diffusion process, \texttt{DDS2M} enjoys stronger generalization ability to various HSIs compared to existing diffusion-based methods and superior robustness to noise compared to existing HSI restoration methods. Extensive experiments on HSI denoising, noisy HSI completion and super-resolution on a variety of HSIs demonstrate \texttt{DDS2M}’s superiority over the existing task-specific state-of-the-arts.
PDF 11 pages, 5 figures, conference
点此查看论文截图
DR2: Diffusion-based Robust Degradation Remover for Blind Face Restoration
Authors:Zhixin Wang, Xiaoyun Zhang, Ziying Zhang, Huangjie Zheng, Mingyuan Zhou, Ya Zhang, Yanfeng Wang
Blind face restoration usually synthesizes degraded low-quality data with a pre-defined degradation model for training, while more complex cases could happen in the real world. This gap between the assumed and actual degradation hurts the restoration performance where artifacts are often observed in the output. However, it is expensive and infeasible to include every type of degradation to cover real-world cases in the training data. To tackle this robustness issue, we propose Diffusion-based Robust Degradation Remover (DR2) to first transform the degraded image to a coarse but degradation-invariant prediction, then employ an enhancement module to restore the coarse prediction to a high-quality image. By leveraging a well-performing denoising diffusion probabilistic model, our DR2 diffuses input images to a noisy status where various types of degradation give way to Gaussian noise, and then captures semantic information through iterative denoising steps. As a result, DR2 is robust against common degradation (e.g. blur, resize, noise and compression) and compatible with different designs of enhancement modules. Experiments in various settings show that our framework outperforms state-of-the-art methods on heavily degraded synthetic and real-world datasets.
PDF Accepted to CVPR 2023
点此查看论文截图
Synthesizing Realistic Image Restoration Training Pairs: A Diffusion Approach
Authors:Tao Yang, Peiran Ren, Xuansong xie, Lei Zhang
In supervised image restoration tasks, one key issue is how to obtain the aligned high-quality (HQ) and low-quality (LQ) training image pairs. Unfortunately, such HQ-LQ training pairs are hard to capture in practice, and hard to synthesize due to the complex unknown degradation in the wild. While several sophisticated degradation models have been manually designed to synthesize LQ images from their HQ counterparts, the distribution gap between the synthesized and real-world LQ images remains large. We propose a new approach to synthesizing realistic image restoration training pairs using the emerging denoising diffusion probabilistic model (DDPM). First, we train a DDPM, which could convert a noisy input into the desired LQ image, with a large amount of collected LQ images, which define the target data distribution. Then, for a given HQ image, we synthesize an initial LQ image by using an off-the-shelf degradation model, and iteratively add proper Gaussian noises to it. Finally, we denoise the noisy LQ image using the pre-trained DDPM to obtain the final LQ image, which falls into the target distribution of real-world LQ images. Thanks to the strong capability of DDPM in distribution approximation, the synthesized HQ-LQ image pairs can be used to train robust models for real-world image restoration tasks, such as blind face image restoration and blind image super-resolution. Experiments demonstrated the superiority of our proposed approach to existing degradation models. Code and data will be released.
PDF
点此查看论文截图
Parallel Vertex Diffusion for Unified Visual Grounding
Authors:Zesen Cheng, Kehan Li, Peng Jin, Xiangyang Ji, Li Yuan, Chang Liu, Jie Chen
Unified visual grounding pursues a simple and generic technical route to leverage multi-task data with less task-specific design. The most advanced methods typically present boxes and masks as vertex sequences to model referring detection and segmentation as an autoregressive sequential vertex generation paradigm. However, generating high-dimensional vertex sequences sequentially is error-prone because the upstream of the sequence remains static and cannot be refined based on downstream vertex information, even if there is a significant location gap. Besides, with limited vertexes, the inferior fitting of objects with complex contours restricts the performance upper bound. To deal with this dilemma, we propose a parallel vertex generation paradigm for superior high-dimension scalability with a diffusion model by simply modifying the noise dimension. An intuitive materialization of our paradigm is Parallel Vertex Diffusion (PVD) to directly set vertex coordinates as the generation target and use a diffusion model to train and infer. We claim that it has two flaws: (1) unnormalized coordinate caused a high variance of loss value; (2) the original training objective of PVD only considers point consistency but ignores geometry consistency. To solve the first flaw, Center Anchor Mechanism (CAM) is designed to convert coordinates as normalized offset values to stabilize the training loss value. For the second flaw, Angle summation loss (ASL) is designed to constrain the geometry difference of prediction and ground truth vertexes for geometry-level consistency. Empirical results show that our PVD achieves state-of-the-art in both referring detection and segmentation, and our paradigm is more scalable and efficient than sequential vertex generation with high-dimension data.
PDF
点此查看论文截图
Erasing Concepts from Diffusion Models
Authors:Rohit Gandikota, Joanna Materzynska, Jaden Fiotto-Kaufman, David Bau
Motivated by recent advancements in text-to-image diffusion, we study erasure of specific concepts from the model’s weights. While Stable Diffusion has shown promise in producing explicit or realistic artwork, it has raised concerns regarding its potential for misuse. We propose a fine-tuning method that can erase a visual concept from a pre-trained diffusion model, given only the name of the style and using negative guidance as a teacher. We benchmark our method against previous approaches that remove sexually explicit content and demonstrate its effectiveness, performing on par with Safe Latent Diffusion and censored training. To evaluate artistic style removal, we conduct experiments erasing five modern artists from the network and conduct a user study to assess the human perception of the removed styles. Unlike previous methods, our approach can remove concepts from a diffusion model permanently rather than modifying the output at the inference time, so it cannot be circumvented even if a user has access to model weights. Our code, data, and results are available at https://erasing.baulab.info/
PDF
点此查看论文截图