2022-08-15 更新
Image Translation Based Nuclei Segmentation for Immunohistochemistry Images
Authors:Roger Trullo, Quoc-Anh Bui, Qi Tang, Reza Olfati-Saber
Numerous deep learning based methods have been developed for nuclei segmentation for H&E images and have achieved close to human performance. However, direct application of such methods to another modality of images, such as Immunohistochemistry (IHC) images, may not achieve satisfactory performance. Thus, we developed a Generative Adversarial Network (GAN) based approach to translate an IHC image to an H&E image while preserving nuclei location and morphology and then apply pre-trained nuclei segmentation models to the virtual H&E image. We demonstrated that the proposed methods work better than several baseline methods including direct application of state of the art nuclei segmentation methods such as Cellpose and HoVer-Net, trained on H&E and a generative method, DeepLIIF, using two public IHC image datasets.
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Scale-free Photo-realistic Adversarial Pattern Attack
Authors:Xiangbo Gao, Weicheng Xie, Minmin Liu, Cheng Luo, Qinliang Lin, Linlin Shen, Keerthy Kusumam, Siyang Song
Traditional pixel-wise image attack algorithms suffer from poor robustness to defense algorithms, i.e., the attack strength degrades dramatically when defense algorithms are applied. Although Generative Adversarial Networks (GAN) can partially address this problem by synthesizing a more semantically meaningful texture pattern, the main limitation is that existing generators can only generate images of a specific scale. In this paper, we propose a scale-free generation-based attack algorithm that synthesizes semantically meaningful adversarial patterns globally to images with arbitrary scales. Our generative attack approach consistently outperforms the state-of-the-art methods on a wide range of attack settings, i.e. the proposed approach largely degraded the performance of various image classification, object detection, and instance segmentation algorithms under different advanced defense methods.
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